Aloprim

Aloprim is a prescription medication used to lower high levels of uric acid in the body due to cancer treatment. Aloprim belongs to a group of drugs call xanthine oxidase inhibitors, which work by decreasing uric acid in the body. High levels of uric acid may lead to gout attacks or kidney stones.

Aloprim is available as an injectable form to be given into the vein (IV) by healthcare professional.

Common side effects of Aloprim include nausea, rash, and vomiting.

Aloprim is also used to lower high levels of uric acid in the body due to cancer treatment.

This medication may be prescribed for other uses. Ask your doctor or pharmacist for more information.

• Bioniche Pharma USA LLC

• Mylan Institutional, Inc.

Aloprim may cause side effects. Tell your doctor if any of these symptoms are severe or do not go away:

• rash
• kidney failure
• local injection site reaction
• nausea (upset stomach)
• vomiting

This is not a complete list of Aloprim drug interactions. Ask your doctor or pharmacist for more information.

Tell your doctor about all the medicines you take including prescription and non-prescription medicines, vitamins, and herbal supplements. Especially tell your doctor if you take:

• an ACE inhibitor
• cyclophosphamide (Cytoxan)
• mercaptopurine (Purinethol)
• azathioprine (Imuran)
• blood thinners such as warfarin (Coumadin, Jantoven)
• chlorpropamide (Diabinese)
• probenecid (Benemid)
• cyclosporine (Neoral, Sandimmune)
• didanosine (Videx, Videx EC)
• sulfinpyrazone (Anturane)
• a diuretic (thiazides)
• ampicillin (Omnipen, Principen, Polycillin)
• amoxicillin (Amoxil, Trimox)

This is not a complete list of Aloprim drug interactions. Ask your doctor or pharmacist for more information.

Serious allergic reactions including death have occurred with Aloprim. Stop taking this medication and talk to your doctor if you develop a skin rash.

Drink plenty of water or other fluids each day while taking Aloprim to prevent kidney stone formation.

Serious liver problems have occurred with Aloprim use. While these events are rare, tell your doctor if you experience weight loss, lack of appetite, and itching. Your doctor will likely run tests to check your liver function.

Kidney failure has occurred in some people who took Aloprim.

Medicines can interact with certain foods. In some cases, this may be harmful and your doctor may advise you to avoid certain foods. In the case of Aloprim there are no specific foods that you must exclude from your diet when receiving Aloprim.

Before receiving Aloprim, tell your doctor about all of your medical conditions including if you:

• have liver or kidney disease
• are pregnant or breastfeeding
• are allergic to any medications, foods, dyes or preservatives

Tell your doctor about all the medicines you take including prescription and non-prescription medicines, vitamins, and herbal supplements.

Tell your doctor if you are pregnant or plan to become pregnant.

The FDA categorizes medications based on safety for use during pregnancy. Five categories - A, B, C, D, and X, are used to classify the possible risks to an unborn baby when a medication is taken during pregnancy.

Aloprim falls into category C. There are no good studies that have been done in humans with Aloprim. In animals studies, pregnant animals were given this medication and had some babies born with problems. However, this medication may sometimes still help human mothers and their babies more than it might cause harm.

Tell your doctor if you are breastfeeding or plan to breastfeed. Aloprimis found in breastmilk. Since the effect of Aloprim on the nursing infant is unknown, caution should be used when Aloprim is given to a nursing woman.

Aloprim is available as an injectable form to be given into the vein (IV) by healthcare professional.

If you miss a dose, be sure to make a follow up appointment.

Take Aloprim exactly as prescribed.

The dose your doctor recommends may be based on the following:

• the condition being treated
• other medications you are taking
• other conditions you have
• how your body responds to Aloprim
• your kidney function

The recommended daily dose of Aloprim for adults is 200 to 400 mg/m²/day. The maximum daily dose is 600 mg.

The recommended starting daily dose of Aloprim for children is 200 mg/m²/day.

Since Aloprim is administered by a healthcare provider in a medical setting, it is unlikely that an overdose will occur. However, if overdose is suspected, seek emergency medical attention.