Tezspire

Tezspire is a prescription medicine used with other asthma medicines for the maintenance treatment of severe asthma in people 12 years of age and older. Tezspire helps prevent severe asthma attacks (exacerbations) and can improve your breathing.

Tezspire belongs to a group of drugs called TSLP blockers. It is believed to work by targeting and blocking TSLP, a key substance that initiates an overreactive immune response to a variety of types of airway inflammation associated with severe asthma.

Tezspire is injected under your skin (subcutaneously) 1 time every 4 weeks, in a healthcare setting.

Common side effects include sore throat, back pain and joint pain.

Tezspire is a prescription medicine used with other asthma medicines for the maintenance treatment of severe asthma in people 12 years of age and older whose asthma is not controlled with their current asthma medicine.

Tezspire helps prevent severe asthma attacks (exacerbations) and can improve your breathing.

Tezspire is not used to treat sudden breathing problems. Tell your healthcare provider if your asthma does not get better or if it gets worse after you start treatment with Tezspire.

It is not known if Tezspire is safe and effective in children under 12 years of age.

This medication may be prescribed for other uses. Ask your doctor or pharmacist for more information.

Serious side effects have been reported with Tezspire. See "Tezspire Precautions" section.

Common side effects of Tezspire include:

• sore throat
• joint pain
• back pain

These are not all of the possible side effects of Tezspire. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Tell your healthcare provider about all the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements.

Do not change or stop your corticosteroid medicines or other asthma medicines unless your healthcare provider tells you to.

Tezspire may cause serious side effects, including:

• severe allergic reactions. Call your healthcare provider or get emergency medical care if you get any of the following symptoms of allergic reaction:
  • rash
  • hives
  • breathing problems
  • red, itchy, swollen or inflamed eyes

Do not receive Tezspire if you:

• are allergic to tezepelumab or any of the ingredients in Tezspire. 

Medications can interact with certain foods. In some cases, this may be harmful and your doctor may advise you to avoid certain foods. In the case of Tezspire, there are no specific foods that you must exclude from your diet when receiving this medication.

Before you receive Tezspire, tell your healthcare provider about all of your medical conditions, including if you:

• have ever had a severe allergic reaction (hypersensitivity).
• have a parasitic (helminth) infection.
• have recently received or are scheduled to receive any live attenuated vaccinations. People who receive Tezspire should not receive live attenuated vaccines.
• are pregnant, think you may be pregnant, or plan to become pregnant. It is not known if Tezspire may harm your unborn baby.
• are breastfeeding or plan to breastfeed. It is not known if Tezspire passes into your breast milk. Talk to your healthcare provider about the best way to feed your baby if you receive Tezspire.

Tell your doctor about all the medicines you take including prescription and non-prescription medicines, vitamins, and herbal supplements.

Tell your doctor if you are pregnant, think you may be pregnant, or plan to become pregnant. It is not known if Tezspire may harm your unborn baby.

Tell your doctor if you are breastfeeding or plan to breastfeed. It is not known if Tezspire passes into your breast milk. Talk to your healthcare provider about the best way to feed your baby if you receive Tezspire.

• Your healthcare provider will give you Tezspire in a healthcare setting. 
• Tezspire is injected under your skin (subcutaneously) 1 time every 4 weeks.
• If you miss an appointment, ask your healthcare provider when to schedule your next treatment.

The recommended Tezspire dosage is 210 mg administered once every 4 weeks.