Triazolam

Triazolam is a prescription medication used for short-term treatment of insomnia (generally 7–10 days). It is not meant to be used by children. Triazolam belongs to a group of medications called benzodiazepines and works by decreasing the activity of brain, resulting in a sedative effect.

Triazolam comes in a tablet form, and is to be taken once daily by mouth at night just before sleep.

Common side effects of triazolam include headache, lightheadedness, and tingling sensations on the skin.

Triazolam can cause drowsiness. Do not drive or operate heavy machinery until you know how this medication will affect you.

Triazolam is a prescription medicine used in adults for the short-term treatment (usually 7-10 days) of insomnia. It is not meant to be used by children.

This medication may be prescribed for other uses. Ask your doctor or pharmacist for more information.

Triazolam may be found in some form under the following brand names:

• Halcion

Serious side effects have been reported with triazolam. See “Drug Precautions” section.

Common side effects of triazolam include:

• drowsiness
• headache
• dizziness
• lightheadedness
• "pins and needles" feelings on your skin
• difficulty with coordination
• You may still feel drowsy the next day after taking triazolam. Do not drive or do other dangerous activities (including operating machinery) after taking triazolam until you feel fully awake.
• You may have withdrawal symptoms for 1 to 2 days when you stop taking triazolam suddenly. Withdrawal symptoms include trouble sleeping, unpleasant feelings, stomach and muscle cramps, vomiting, sweating, shakiness, and seizures.

These are not all the side effects of triazolam. Ask your doctor or pharmacist for more information.

Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Tell your doctor about all of the medicines you take including prescription and nonprescription medicines, vitamins and herbal supplements.

Medicines can interact, sometimes causing side effects. 

Do not take triazolam with other medicines that can make you sleepy including alcohol, antidepressant medications, antipsychotic medications, barbiturates, narcotic or opiod pain medicines, other benzodiazepines, seizure medicines, muscle relaxants, and other sleep medicines. Combining these medicines with triazolam can increase your risk of side effects such as drowsiness, confusion, memory loss, and difficulty breathing.

Other medicines may interact with triazolam by increasing the amount of triazolam in your blood, increasing your risk of side effects. Tell your doctor if you take:

• birth control pills
• cimetidine (Tagamet)
• clarithromycin (Biaxin)
• delavirdine (Rescriptor)
• erythromycin (Ery-Tab, Erythrocin, E-mycin)
• grapefruit and grapefruit juice
• isoniazid (Nydrazid)
• itraconazole (Sporanox)
• ketoconazole (Nizoral)
• miconazole (Monistat, Micatin)
• nefazodone (Serzone)
• protease inhibitors such as amprenavir (Agenerase), atazanavir (Reyataz), fosamprenavir (Lexiva), indinavir (Crixivan), nelfinavir (Viracept), ritonavir (Norvir), saquinavir (Invirase)
• ranitidine (Zantac)
• telithromycin (Ketek)

This is not a complete list of triazolam drug interactions. Ask your doctor or pharmacist for more information. Know the medicines you take. Keep a list of your medicines with you to show your doctor and pharmacist each time you get a new medicine.

After taking triazolam, you may get up out of bed while not being fully awake and do an activity that you do not know you are doing. The next morning, you may not remember that you did anything during the night. You have a higher chance for doing these activities if you drink alcohol or take other medicines that make you sleepy with triazolam. Reported activities include:

• driving a car ("sleep-driving")
• making and eating food
• talking on the phone
• having sex
• sleep-walking

Triazolam is not indicated for use in children.

Elderly patients are especially susceptible to dose related adverse effects when taking triazolam.

1.  Take triazolam exactly as prescribed

• Do not take more triazolam than prescribed.
• Take triazolam right before you get in bed, not sooner.

2.  Do not take triazolam if you:

• drink alcohol
• take other medicines that can make you sleepy. Talk to your doctor about all of your medicines. Your doctor will tell you if you can take triazolam with your other medicines
• cannot get a full night's sleep
• are pregnant or considering becoming pregnant

3.  Call your doctor right away if you find out that you have done any of the above activities after taking triazolam.

Do not take this medication if you are allergic to triazolam.

Grapefruit and grapefruit juice may interact with triazolam and lead to potentially dangerous effects. Discuss the use of grapefruit products with your doctor.

Triazolam may not be right for you. Before starting triazolam, tell your doctor about all of your health conditions, including if you:

• have a history of depression, mental illness, or suicidal thoughts
• have a history of drug or alcohol abuse or addiction
• have kidney or liver disease
• have a lung disease or breathing problems
• are pregnant, planning to become pregnant, or breastfeeding

Tell your doctor about all of the medicines you take including prescription and nonprescription medicines, vitamins and herbal supplements. Medicines can interact, sometimes causing side effects. Do not take triazolam with other medicines that can make you sleepy.

Tell your doctor if you are pregnant or plan to become pregnant. Triazolam increases the risk of birth defects and withdrawal symptoms in newborns. Triazolam should not be taken during pregnancy.

Tell your doctor if you are breastfeeding or plan to breastfeed. It is not known if triazolam is excreted in human breast milk or if it will harm your nursing baby.

• Take triazolam exactly as prescribed. Do not take more triazolam than prescribed for you.
• Take triazolam right before you get into bed, or you can take the triazolam after you have been in bed and have trouble falling asleep.
• Do not take triazolam with or right after a meal.
• Do not take triazolam unless you are able to get a full night's sleep before you must be active again.
• Call your healthcare provider if your insomnia worsens or is not better within 7 to 10 days. This may mean that there is another condition causing your sleep problem.

Take this medication exactly as prescribed by your doctor. Follow the directions on your prescription label carefully.

The dose your doctor recommends may be based on the following:

• the condition being treated
• other medical conditions you have
• other medications you are taking
• how you respond to this medication
• your age

The recommended dose range of triazolam for the treatment of short-term treatment of insomnia is 0.125 mg- 0.5 mg. A dose of 0.5 mg should not be exceeded.

If you take too much triazolam or overdose, call your doctor or poison control center right away, or get emergency treatment.

• Store triazolam at room temperature between 68° and 77° F (20° to 25°C).
• Protect from light.
• Keep triazolam and all medicines out of the reach of children.
• Do not use triazolam after the expiration date on the bottle.