Oxytrol

Oxytrol is a prescription medication used to treat overactive bladder. Oxytrol belongs to a group of drugs called antispasmodics, which help to relax the bladder muscle. 

This medication comes in a transdermal (patch) form and is applied twice a week (every 3-4 days).

Common side effects of Oxytrol include dry mouth and application site reactions. Oxytrol can also cause blurred vision, drowsiness, and dizziness. Do not drive or operate heavy machinery until you know how Oxytrol affects you.

Oxytrol is a prescription medication used to treat overactive bladder. Symptoms treated are:

• Painful, frequent urination
• Urination leaking accidents

This medication may be prescribed for other uses. Ask your doctor or pharmacist for more information.

• Actavis Pharma, Inc.

Serious side effects have been reported with Oxytrol. See the "Oxytrol precautions" section. Common side effects of Oxytrol include the following:

• Localized redness and swelling, itching
• Diarrhea

This is not a complete list of Oxytrol side effects. Ask your doctor or pharmacist for more information. Tell your doctor if you have any side effect that bothers you or that does not go away. Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

Tell your doctor about all the medications you take, including prescription and non-prescription medicines, vitamins, and herbal supplements. Especially tell your doctor if you take:

• ipratropium oral inhalation (Atrovent HFA), tiotropium oral inhalation (Spiriva HandiHaler)
• potassium chloride (Klor-Con)
• chlorpheniramine (Chlor-Trimeton), diphenhydramine (Benadryl)
• amitriptyline (Elavil), clomipramine (Anafranil), imipramine (Tofranil)
• Opioid medications such as morphine (MS Contin), hydromorphone (Dilaudid), oxycodone (Oxycontin), methadone (Dolophine), and combination opioid medications such as hydrocodone-acetaminophen (Lorcet, Lortab, Vicodin, Norco), oxycodone-acetaminophen (Endocet, Percocet), and acetaminophen-codeine (Tylenol #3)
• Medications that use the enzyme CYP3A4, such as ketoconazole (Nizoral), itraconazole (Sporanox), miconazole (Lotrimin, Vagistat), erythromycin (E.E.S. granules), clarithromycin (Biaxin)
• Medications that are classified as acetylcholinesterase inhibitors, such as donepezil (Aricept), galantamine (Razadyne), and rivastigmine (Exelon)

This is not a complete list of Oxytrol drug interactions. Ask your doctor or pharmacist for more information.

Serious side effects have been reported with Oxytrol, including the following:

• Central nervous system effects. These may include hallucinations, agitation, confusion, and drowsiness.
• Angioedema. If you experience swelling of your face, lips, tongue, or larynx after taking Oxytrol, call 911 for prompt medical attention.
• Heat prostration. This would include fever and heat stroke due to decreased sweating. This can occur if Oxytrol is taken in the presence of high environmental temperature.

Transdermal patch: Remove patch before an MRI.

Oxytrol can cause drowsiness. Do not drive or operate heavy machinery until you know how Oxytrol affects you.

Do not take Oxytrol if you:

• Are allergic to Oxytrol or to any of its ingredients
• If you have, or are at risk for uncontrolled narrow-angle glaucoma, urinary retention, gastric retention, or conditions with very decreased gastrointestinal movement

Medications can interact with certain foods.  In some cases, this may be harmful and your doctor may advise you to avoid certain foods. In the case of Oxytrol, there are no specific foods that you must exclude from your diet while receiving this medication.

Before taking Oxytrol, tell your doctor about all of your medical conditions. Especially tell your doctor if you:

• Are allergic to Oxytrol or any of its ingredients
• Have or have had hyperthyroidism, coronary heart disease, congestive heart failure, cardiac arrhythmias, hiatal hernia, tachycardia (rapid heart beat), hypertension, myasthenia gravis, and prostatic hypertrophy (enlargement of the prostate gland)
• Have problems with your liver or kidney
• Have a blockage preventing urine flowing out from your bladder
• Have a blockage in your stomach or intestines, or have ulcerative colitis or gastroesophageal reflux disease (GERD)

Tell your doctor about all the medicines you take including prescription and non-prescription medicines, vitamins, and herbal supplements.

Tell your doctor if you are pregnant or plan to become pregnant.  The FDA categorizes medications based on safety for use during pregnancy. Five categories - A, B, C, D, and X, are used to classify the possible risks to an unborn baby when a medication is taken during pregnancy. 

Oxytrol falls into category B. There are no well-done studies that have been done in humans with Oxytrol. In animal studies, pregnant animals were given this medication, and the babies did not show any medical issues related to this medication.

Tell your doctor if you are breastfeeding or plan to breastfeed. It is not known if Oxytrol crosses into human milk. Because many medications can cross into human milk and because of the possibility for serious adverse reactions in nursing infants with use of this medication, a choice should be made whether to stop nursing or stop the use of this medication. Your doctor will decide if the benefits outweigh the risks of using Oxytrol.

Apply Oxytrol exactly as prescribed.

Oxytrol comes as a transdermal (patch) form and is applied twice a week (every 3-4 days).

Apply Oxytrol  to clean, dry skin on abdomen, hip, or buttock. Select a new site for each new system (avoid reapplication to same site within 7 days). Wear patch under clothing; do not expose to sunlight.

Alcohol may intensify the effect of this medication.

If you miss a dose, take the missed dose as soon as you remember. If it is almost time for the next dose, skipped the missed dose and take your next dose at the regular time. Do not apply two doses of Oxytrol at the same time.

Apply this medication exactly as prescribed by your doctor. Follow the directions on your prescription label carefully. 

The dose your doctor recommends may be based on the following:

• the condition being treated
• other medical conditions you have
• other medications you are taking
• how you respond to this medication
• your weight
• your height
• your age
• your gender

The recommended dose of Oxytrol (oxybutynin) is one 3.9 mg/day patch twice weekly (every 3-4 days).

If you apply too much Oxytrol, call your healthcare provider or local Poison Control Center, or seek emergency medical attention right away. If Oxytrol is administered by a healthcare provider in a medical setting, it is unlikely that an overdose will occur. However, if an overdose is suspected, seek emergency medical attention.